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Orlistat Medication Information Leaflet

Common Use

Orlistat is used for weight management in individuals with obesity or overweight, in combination with a reduced-calorie diet.

Generic Ingredient

The generic compound for Orlistat is also known as Orlistat and is available in Canada.

Classification

Orlistat is classified as a gastrointestinal lipase inhibitor.

Certification Information

Orlistat is approved in various countries including the United States, Canada, and the European Union.

Known Alternatives in Canada

Some alternatives to Orlistat in Canada include liraglutide, phentermine-topiramate, and naltrexone-bupropion.

Clinical Use

Orlistat is clinically used to promote weight loss by reducing the absorption of fat in the intestines.

Spectrum Of Activity

Orlistat specifically targets and inhibits the absorption of dietary fats.

Drug interaction

Orlistat may interact with some medications such as cyclosporine, levothyroxine, and anticoagulants. It is essential to consult a healthcare professional before using Orlistat with other medications.

Dosage and Directions

The recommended dosage of Orlistat is 120 mg to be taken orally three times a day with each main meal containing fat. It should be taken within one hour of the meal or up to an hour after the meal.

Contraindications and Precautions

Orlistat is contraindicated in individuals with chronic malabsorption syndrome or cholestasis. Precautions should be taken in individuals with a history of kidney stones, as Orlistat may increase the risk of kidney stones.

Possible side effect

Common side effects of Orlistat include oily spotting, flatulence with discharge, and fecal urgency. It may also cause deficiency of fat-soluble vitamins if used long-term.

Missed dose and Overdose

If a dose of Orlistat is missed, it can be taken within an hour of your last meal. In the case of an overdose, it is advised to seek medical attention.

Storage

Orlistat should be stored at room temperature, away from moisture and heat.

Special Cases

For individuals with diabetes, close monitoring of blood sugar levels is advised when taking Orlistat, as it may affect blood sugar control.

Known Non-standard Use

Some non-standard uses of Orlistat include its potential in the management of polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD). However, further research is needed in these areas.

Patient Considerations

Patients should be advised to adhere to a reduced-calorie diet while taking Orlistat and to increase physical activity for optimal weight management.

Possible Risks

There are potential risks of gastrointestinal adverse effects, as well as the risk of decreased absorption of fat-soluble vitamins. Close monitoring and appropriate supplementation may be required.

Breastfeeding and Pregnancy

Orlistat is not recommended during pregnancy or breastfeeding, as its safety under these conditions has not been established.

Orlistat FAQ

How does Orlistat work?

Orlistat works by inhibiting the absorption of dietary fats in the body, thus reducing calorie intake.

What is the recommended dosage of Orlistat?

The recommended dosage of Orlistat is 120 mg taken with each main meal containing fat.

What are the potential side effects of Orlistat?

Common side effects of Orlistat include gastrointestinal issues such as oily spotting, flatulence, and fecal urgency.

Can Orlistat be taken by pregnant women?

Pregnant women should not take Orlistat as it could harm the unborn baby.

How long does it take for Orlistat to show results?

Orlistat may start showing results within 2 weeks of starting the treatment, but it may take longer for significant weight loss.

Is it safe to take Orlistat with other medications?

It's important to consult a healthcare professional before taking Orlistat with other medications to prevent potential interactions.

What dietary precautions should be taken while using Orlistat?

When using Orlistat, it's essential to follow a low-fat diet to minimize the occurrence of gastrointestinal side effects.

Can Orlistat be taken by children?

Orlistat is not recommended for use in children under 12 years old without medical supervision.

Does Orlistat affect birth control?

Orlistat may decrease the effectiveness of hormonal contraceptives, so alternative birth control methods should be considered.

What is the mechanism of action of Orlistat?

Orlistat works in the gastrointestinal tract by blocking the action of lipase enzymes, which are responsible for breaking down dietary fats.

What should I do if I miss a dose of Orlistat?

If a dose of Orlistat is missed, it can be taken within 1 hour of a meal, but it should not be taken with a meal that does not contain fat.

Can Orlistat be used for long-term weight management?

Orlistat can be used for long-term weight management, but it should be combined with lifestyle changes such as a healthy diet and regular exercise.

Is Orlistat available over the counter?

Orlistat is available both over the counter and with a prescription, depending on the dosage strength.

What are the key considerations before starting Orlistat?

Before starting Orlistat, it's important to inform the healthcare provider about any pre-existing medical conditions, current medications, and allergies.

Can Orlistat be used for individuals with diabetes?

Orlistat can be used by individuals with diabetes, but close monitoring of blood sugar levels is necessary as the medication may affect insulin requirements.