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Zyban Medication Information Leaflet

Common Use

Zyban is commonly used as an aid to help people stop smoking by reducing withdrawal effects and the urge to smoke.

Generic Ingredient

The generic ingredient for Zyban is bupropion hydrochloride. It is available in Canada.

Classification

Zyban belongs to the class of medications called antidepressants.

Certification Information

Zyban is approved for use in various countries, including Canada, the United States, and the United Kingdom.

Known Alternatives in Canada

Some alternatives to Zyban in Canada include nicotine replacement therapies (e.g., patches, gum) and prescription medications (e.g., varenicline).

Clinical Use

Zyban is clinically used to aid smoking cessation and to reduce withdrawal symptoms associated with nicotine addiction.

Spectrum Of Activity

Zyban's activity is primarily focused on reducing cravings for nicotine and minimizing the withdrawal symptoms associated with quitting smoking.

Drug interaction

Zyban may interact with certain medications, including MAO inhibitors, SSRIs, and drugs that lower the seizure threshold. It is important to consult a healthcare professional regarding potential drug interactions.

Dosage and Directions

The recommended initial dose of Zyban is 150 mg once daily for the first 3 days, followed by a dose of 150 mg twice daily. It should be started 1-2 weeks before the quit date. The maximum dose should not exceed 300 mg per day.

Contraindications and Precautions

Zyban is contraindicated in patients with a seizure disorder, current or past diagnosis of bulimia or anorexia nervosa, and in patients undergoing abrupt discontinuation of alcohol or sedatives. Precautions should be taken in patients with certain medical conditions and in those taking other medications.

Possible side effect

Common side effects of Zyban may include dry mouth, insomnia, headache, and nausea. Serious side effects such as seizures are rare but may occur.

Missed dose and Overdose

If a dose of Zyban is missed, it should be taken as soon as remembered. However, the dose should not be doubled. In case of an overdose, seek immediate medical attention or contact a poison control center.

Storage

Zyban should be stored at room temperature in a tightly closed container, away from moisture and heat.

Special Cases

Special consideration should be given when prescribing Zyban to patients with underlying psychiatric conditions, such as depression or anxiety. Close monitoring is essential during treatment with Zyban.

Known Non-standard Use

Zyban may be used off-label in the treatment of depression, seasonal affective disorder, and attention-deficit hyperactivity disorder (ADHD).

Patient Considerations

Patients should be advised to inform their healthcare provider about their complete medical history, including any psychiatric disorders, as well as all medications and supplements they are currently taking.

Possible Risks

There is a risk of psychiatric symptoms and an increased risk of suicidal thinking and behavior in patients treated with Zyban. Patients should be closely monitored for any changes in mood or behavior.

Breastfeeding and Pregnancy

Zyban should be used with caution during pregnancy and breastfeeding. The potential risks and benefits should be discussed with a healthcare professional before use.

Zyban FAQ

What is Zyban used for?

Zyban is used to help people stop smoking by reducing cravings and withdrawal effects.

What are the side effects of Zyban?

Common side effects may include dry mouth, trouble sleeping, dizziness, nausea, and changes in appetite.

How long does it take for Zyban to work?

It may take about 1 week for Zyban to reach its full effect. It is important to follow the prescribed dosage and not to stop suddenly.

Can Zyban be used for depression?

Zyban is not approved to treat depression, but it is sometimes used off-label to help with symptoms of depression.

Is Zyban the same as Wellbutrin?

Yes, Zyban is the brand name for the generic drug bupropion, which is also sold under the brand name Wellbutrin for treating depression.

Can Zyban cause weight loss?

Weight loss is a possible side effect of Zyban, but individual responses may vary.

How is Zyban different from nicotine replacement therapy?

Zyban works in the brain to reduce nicotine cravings and withdrawal symptoms, while nicotine replacement therapy provides the body with nicotine to reduce these symptoms.

Can Zyban be used with nicotine patches?

It is possible to use Zyban with nicotine patches, but this combination should be done under the guidance of a healthcare professional.

Can Zyban be used by pregnant women?

It is important to consult a healthcare provider before using Zyban during pregnancy, as the potential risks and benefits need to be carefully considered.

What should I do if I miss a dose of Zyban?

If you miss a dose of Zyban, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with the regular dosing schedule.

How long should I take Zyban?

The duration of Zyban treatment varies from person to person, but it is generally recommended to take it for 7 to 12 weeks.

Can Zyban be used for other addictions?

While Zyban is primarily used to help with smoking cessation, it has also shown some effectiveness in the treatment of other addictions, but this should only be done under medical supervision.

Is Zyban addictive?

Zyban is not habit-forming, and it does not lead to physical dependence.

How does Zyban compare to Chantix?

Both Zyban and Chantix are prescription medications used to help with smoking cessation, but they work in different ways and have different potential side effects.